The ASTRIDE Study and the 302 Study

These studies are looking at a new investigational drug, serplulimab, in adults (people 18 and older) who have either extensive-stage small cell lung cancer or limited-stage small cell lung cancer. The goal is to see if serplulimab can help patients live longer without their cancer spreading.

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Astride logo

Extensive-Stage Small Cell Lung Cancer (ES-SCLC)

The ASTRIDE Study is testing an investigational drug to see if it can help adults with ES-SCLC. Researchers want to compare the effectiveness of the study drug + chemotherapy with the effectiveness of an already approved drug (atezolizumab) + chemotherapy.

Who Can Join?arrow
Who can join the ASTRIDE study?

Who can join the ASTRIDE study?

The ASTRIDE Study is for adults that have been diagnosed with extensive-stage small cell lung cancer (ES-SCLC), and meet the following criteria*:

checkmarkAre 18 years of age or older.
checkmarkHave been diagnosed with ES-SCLC.
checkmarkHave NOT already received treatment for ES-SCLC

*Other criteria also apply.

If you received one cycle of chemotherapy for newly diagnosed ES-SCLC as continued treatment, you may be eligible. If you have received chemoradiotherapy for limited-stage SCLC, it must have taken place more than 6 months before starting this study.

Henlius USA Inc., the sponsor of these studies, will pay for the cost of medications received as part of the clinical study, as well as the cost of travel, accommodations, and meals.

Henlius logo

Limited-Stage Small Cell Lung Cancer (LS-SCLC)

The Henlius 302 Study is testing an investigational drug in combination with chemotherapy and radiation to see if it can help adults with LS-SCLC. Researchers want to compare the effectiveness of the study drug + chemotherapy + radiation with those of chemotherapy + radiation alone (standard therapy for LS-SCLC).

Who Can Join?arrow
Who can join the 302 study?

Who can join the 302 study?

The Henlius 302 Study is for adults that have been diagnosed with limited-stage small cell lung cancer (LS-SCLC), and meet the following criteria*:

checkmark Are 18 years of age or older.
checkmark Have a diagnosis of LS-SCLC.
checkmark Are NOT eligible for surgery or do not wish to have surgery.
checkmark Have NOT already received treatment for SCLC

*Other criteria may also apply.

Find a Study Site

Our clinical studies for SCLC are currently recruiting patients. Enter a zip code below to find a study site that is convenient for you.

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Pontchartrain Cancer Center

15799 Professional Plaza
Hammond, LA 70433

Napa Research

5667 NW 29th St.
Margate, FL 33063

The University of Texas Health Science Center at Tyler/HOPE Cancer Center

721A Clinic Drive
Tyler, TX 75701

American Oncology Network Vista Oncology Division

141 Lilly Rd NE
Olympia, WA 98506

Health Partners Cancer Center at Regions Hospital

640 Jackson Street
St. Paul, MN 55101

Mid Florida Hemotology and Oncology Center

2776 Enterprise Road
Orange City, FL 32763

Cleveland Clinic Mercy Hospital

1320 Mercy Drive N.W.
Canton, OH 44708

The Center for Cancer and Blood Disorders

800 W. Magnolia Ave Suite 230
Fort Worth, TX 76104

Kaiser Permanente Research (Southern California)

4647 Zion Ave. Rm 2425
Los Angeles, CA 90034

Valley Cancer Associates

1719 Treasure Hills Boulevard
Harlingen, TX 78550

Highlands Oncology Group

3901 Parkway Circle
Springdale, AR 72762

CTCA- Chicago

2520 Elisha Ave
Zion, IL 60099

City of Hope - Phoenix

14200 W. Celebrate Life Way
Goodyear, AZ 85338

St. Vincent Frontier Cancer Center

1315 Golden Valley Circle
Billings, MT 59102

Tricounty Hematology and Oncology Associates

7337 Caritas Circle N.W. Suite 150
Massillon, OH 44646

Northwest Medical Specialties, PLLC

1624 South Street Suite 407
Tacoma, WA 98405

Tulane Medical Center

333 S. Liberty Street JBJ 1A Mezzanine
New Orleans, LA 70112

Advanced Research

7431 N University Dr STE 110
Tamarac, FL 33321

Dartmouth Hitchcock Medical Center

1 Medical Center Dr
Lebanon, NH 3756

Millenium Research and Clinical Development

522 Timberdale Ln
Houston, TX 77090

Renown Health

1155 Mill St. O14
Reno, NV 89502

Compassionate Care Research Group

11180 Warner Ave Suite 351
Fountain Valley, CA 92708

MidAmerica Division Inc., c/o Research Medical Center

2316 E Meyer Blvd A Level
Kansas City, MO 64132

Great Lakes Cancer Care (Kaleida Health)

45 Spindrift Drive
Williamsville, NY 14221

Long Beach Memorial Medical Center

2801 Atlantic Avenue
Long Beach, CA 90806

BRCR Glocal

8200 W Sunrise Blvd Suite D-2
Plantation, FL 33322

CHRISTUS Institute for Innovation & Advanced Clinical Care

1415 Santa Fe Ste C
Corpus Christi, TX 78404

Gabrail Cancer Center (GCC) Research- Canton Facility

4875 Higbee Ave. NW
Canton, OH 44718

Florida Cancer Affiliates -  Ocala - Main (Ocala Oncology - Ocala)

3130 SW 32nd Avenue
Ocala, FL 34474

University of Wisconsin Carbone Cancer Center

600 Highland Avenue E5/125-1530
Madison, WI 53792

CHRISTUS St. Vincent

490A West Zia Rd
Santa Fe, NM 87505

Froedtert Hospital- Medical College of Wisconsin

9200 W Wisconsin Ave Rm 3147
Milwaukee, WI 53226

OPN - Oncology Physician Network

622 West Duarte Road Suite 202
Arcadia, CA 91107

OPN - Oncology Physician Network

3851 Katella Avenue Suite 125
Los Alamitos, CA 90720

Summa Health

525 E. Market Street
Akron, OH 44304

California Research Institute

1300 N. Vermont Avenue Suite 606
Los Angeles, CA 90027

Lumi Research

22751 Professional Drive #240
Kingwood, TX 77339

Oncology Hematology Associates

3850 S. National Ave Suite 600
Springfield, MO 65807

Regional Cancer Care Associates LLC RCCA

326 Professional View Drive
Freehold, NJ 7728

DHR Research

5501 S Mccoll Rd
Edinburg, TX 78539

Aultman Cancer Center

2600 Sixth Street Southwest
Canton, OH 44710

Utah Cancer Specialists

3838 South 700 East Suite 100
Salt Lake City, UT 84106

Elmhurst (BRANY site)

79-01 Broadway
Elmhurst, NY 11373

UCHealth Memorial Hospital North

1400 E Boulder St
Colorado Springs, CO 80909

Advanced Cancer Treatment Centers

11373 Cortez Blvd Suite 200
Brooksville, FL 34601

Cancer Partners of Nebraska

201 S 68th Street Place Suite 200
Lincoln, NE 68510

Joe Arrington Cancer Research and Treatment Center

4101 22nd Place
Lubbock, TX 79410

Medical Oncology Associates, PS (dba Summit Cancer Centers)

6001 North Mayfair Street
Spokane Valley, WA 99216

The Stamford Hospital

1 Hospital Plaza
Stamford, CT 6904

University Hospitals Cleveland Medical Center

11100 Euclid Avenue
Cleveland, OH 44106

Northwest Oncology and Hematology

3701 Algonquin Rd Suite 900
Rolling Meadows, IL 60008

West Virginia University Cancer Institute

1 Medical Center Dr
Morgantown, WV 26506

Lahey Hospital & Medical Center

41 Mall Road 3 Southeast
Burlington, MA 1805

Ascension Providence Hospital CK Potluri Cancer Center

22301 Foster Winter Drive
Southfield, MI 48075

Hattiesburg Clinic Hematology/Oncology

301 South 28th Avenue
Hattiesburg, MS 39401

Cancer Center of Kansas

818 N. Emporia Ave Suite #403
Wichita, KS 67214

Christus St. Frances Cabrini Cancer Center

3330 Masonic Dr.
Alexandria, LA 71301

Providence Medical Foundation

3555 Round Barn Circle
Santa Rosa, CA 95403

American Oncology Network Vista Oncology Division

141 Lilly Rd NE
Olympia, WA 98506

Health Partners Cancer Center at Regions Hospital

640 Jackson Street
St. Paul, MN 55101

Napa Research

5667 NW 29th St.
Margate, FL 33063

Pontchartrain Cancer Center

15799 Professional Plaza
Hammond, LA 70433

The University of Texas Health Science Center at Tyler/HOPE Cancer Center

721A Clinic Drive
Tyler, TX 75701

AdventHealth

2501 N Orange Ave Suite 689
Orlando, FL 32804

Cancer Specialists of North Florida

7027 A C Skinner Parkway Suite 1
Jacksonville, FL 32256

Cleveland Clinic Mercy Hospital

1320 Mercy Drive NW
Canton, OH 44708

Dartmouth Hitchcock Medical Center

865L Rubin Bldg, One Medical Center Drive
Lebanon, NH 3756

Eastern Connecticut Hematology and Oncology Associates

330 Washington St. Suite 220
Norwich, CT 6360

Gabrail Cancer Center (GCC) Research- Canton Facility

4875 Higbee Ave Nw
Canton, OH 44718

HCA Midwest

2340 East Meyer Blvd Suite 310
Kansas City, MO 64132

Inova Schar Cancer Institute

500 W. 3rd St.
Fairfax, VA 22031

Kaiser Permanente Northwest

3600 N. Interstate Avenue
Portland, OR 97227

Kaiser Permanente Research (Southern California)

6041 Cadillac Avenue
Los Angeles, CA 90034

Lumi Research

22751 Professional Dr Suite 240
Kingwood, TX 77339

Mid Florida Hemotology and Oncology Center

2776 Enterprise Road
Orange City, FL 32763

Millenium Research and Cliinical Development

522 Timberdale Lane
Houston, TX 77090

Montefiore Medical Center

111 East 210th Street
Bronx, NY 10467

Northwest Medical Specialties, PLLC

1624 South I Street Suite #305
Tacoma, WA 98405

OPN - Oncology Physician Network

622 West Duarte Road Suite 202
Arcadia, CA 91107

OPN - Oncology Physician Network

3851 Katella Avenue Suite 125
Los Alamitos, CA 90720

Providence Medical Group

3555 Round Barn Circle
Santa Rosa, CA 90027

Renown Health

1155 Mill Street
Reno, NV 89502

The Center for Cancer and Blood Disorders

800 W. Magnolia Avenue
Fort Worth, TX 76104

The University of Kansas Hospital

2060 W 39th Ave,
Kansas City, KS 66160

Tri-County Hematology & Oncology Associates, Inc.

7337 Caritas Cirrcle Northwest
Massillon, OH 44646

Tulane Medical Center

333 S. Liberty Street JBJ 1A Mezzanine
New Orleans, LA 70112

University of Illinois Cancer Center

914 S Wood St. Rm 237
Chicago, IL 60612

Highlands Oncology Group

3901 Parkway Circle
Springdale, AR 72762

Emad Ibrahim, MD, INC

245 Terracina Blvd Ste 104B
Redlands, CA 92373

R.J. Zuckerberg Cancer Center

450 Lakeville Road
Lake Success, NY 11042

The University of Texas MD Anderson Cancer Center

1515 Holcombe Blvd
Houston, TX 77030

Elmhurst (BRANY site)

79-01 Broadway
Elmhurst, NY 11373

USOR: Sansum Clinic

2040 Viborg Road Suite 140
Solvang, CA 93463

USOR: Maryland Oncology Hematology, P.A.

10710 Charter Drive Suite G020
Columbia, MD 21044

USOR: Rocky Mountain Cancer Centers,LLP

10107 Ridge Gate Parkway Suite 200
Lone Tree, CO 80124

USOR: Texas Oncology, PA/DFW

1609 Hospital Parkway
Bedford, TX 76022

USOR: Texas Oncology Central-South

4101 James Casey Suite 100
Austin, TX 78745

USOR: Illinois Cancer Specialist

8915 W. Golf Road
Niles, IL 60714

USOR: Texas Oncology, PA/Odessa

500 W. 3rd St.
Odessa, TX 79761

USOR: Southern Cancer Center, AL

29653 Anchor Cross Blvd.
Daphne, AL 36526

USOR: Virginia Cancer Center, PC

8613 Route 29
Fairfax, VA 22031

Banner MD Anderson Cancer Center

2000 North Boise Avenue
Loveland, CO 80538

Hope and Healing Cancer Services

950 N. York Rd., Suite 201A
Hinsdale, IL 60621

Lake Regional Health System

54 Hospital Drive
Osage Beach, MO 65065

Monument Health

353 Fairmont Blvd.
Rapid City, SD 57701

Pikeville Hospital

911 Bypass Rd.
Pikeville, KY 41501

UC Davis

2315 Stockton Blvd, Room DT0761
Sacramento, CA 95817

Providence Medical Foundation

2151 N Harbor Blvd. Suite 3200
Fullerton, CA 92835

OneOncology- Eastern Connecticut Hematology and Oncology

330 Washington St. Suite 220
Norwich, CT 06360

OncoHost- St. Luke's of Kansas City

4401 Wornall Rd. East 8
Kansas City, MO 64111

Baptist Health Lexington

1740 Nicholasville Road
Lexington, KY 40503

Clermont Oncology Center

2737 Citrus Tower Blvd.
Clermont, FL 34711

Jersey Shore University Medical Center

1945 Route 33
Neptune City, NJ 07753

NABONC- Alabama Oncology

5000 Medical Way West Suite 610
Bessemer, AL 35022

Los Angeles Cancer Network

15211 Vanowen Street Suites 300 & 210
Van Nuys, CA 91405

Banner MD Anderson Cancer Center (BMDACC)

1801 16th Street
Greeley, CO 80631

Tufts Medicine

800 Washington Street
Boston, MA 02111

Arizona Clinical Research Center (ACRC)

1825 N. Kolb Road
Tuscon, AZ 85715

Willis-Knighton Cancer Center

2600 Kings Hwy. Suite 1001
Shreveport, LA 71103

O'Neal Comprehensive Cancer Center

1802 6th Avenue South
Birmingham, AL 35294

Cancer Specialists of North Florida

7751 Belfort Pkwy Suite 350
Jacksonville, FL 32256

Northwell Health

450 Lakeville Road
Lake Success, NY 11042

University of Nebraska Medical Center

600 South Saddle Creek Road ECI 3002
Omaha, NE 68106

North Mississippi Medical Center Hematology and Oncology Clinic

961 S Gloster Street
Tupelo, MS 38801

CharterCARE (Roger Williams)

825 Chalkstone Ave
Providence, RI 02908

Stony Brook Cancer Center

1 Lauterber Drive Hospital Pavillion Level 5W
Stony Brook, NY 11794

Lake Regional

54 Hospital Drive
Osage Beach, MO 65065

OnCoHost- Northwest Community Healthcare

1001 Calumet Drive Dyer, IN 46311
Dyer, IN 46311

Nebraska Methodist Hospital

8303 Dodge St.
Omaha, NE 68114

Huntsman Cancer Institute

2000 Circle of Hope Drive
Salt Lake City, UT 84112